12-Hydroxylauric Acid - Names and Identifiers
12-Hydroxylauric Acid - Physico-chemical Properties
Molecular Formula | C12H24O3
|
Molar Mass | 216.32 |
Density | 0.988±0.06 g/cm3 (20 ºC 760 Torr) |
Melting Point | 85-88 °C(lit.) |
Boling Point | 296.74°C (rough estimate) |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | White |
BRN | 1238370 |
pKa | 4.78±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Stability | Stable. Incompatible with bases, reducing agents and oxidizing agents. Combustible. May cause dust explosion when mixed with air. |
Refractive Index | 1.4410 (estimate) |
Physical and Chemical Properties | Bioactive 12-Hydroxydodecanoic acid (G12) is an active endogenous metabolite. |
Use | Uses 12-hydroxylauric acid is used for structural and functional characterization of tomato solani s-nitrosoglutathione reductase. |
12-Hydroxylauric Acid - Risk and Safety
Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
12-Hydroxylauric Acid - Upstream Downstream Industry
12-Hydroxylauric Acid - Preparation
P> add chlorinated 12 acid and NaOH solution into the hydrothermal reaction kettle, stop the reaction after hydrothermal alkaline hydrolysis at the specified temperature for a specified time, and filter to obtain crude product of hydroxyl 12 acid. The pure product of end-hydroxy-terminated twelve acid used for structure and purity identification adopts the crude product of end-chlorinated twelve acid first acidified to obtain the crude product of end-hydroxy twelve acid, and then recrystallized and purified by petroleum ether (60~90 ℃). The pure product of end-hydroxy twelve acid used for application performance test is obtained by neutralizing the above. The crude product was treated with boron trifluoride-ether/methanol solution for methyl esterification derivatization, using anhydrous ether extraction, and the upper ether layer was analyzed by GC to analyze the content of each component (area normalization method), and the yield (Y) of the end hydroxyl 12 acid was calculated.
Last Update:2024-04-10 22:29:15